This matchup is not live right now. NFL spreads, totals, the community lean, and player props post as each game approaches. In the meantime:
Indianapolis Colts and Jacksonville Jaguars last played on Sunday, Dec 28, 2025, when the Jacksonville Jaguars won 23–17. Over the last 4 meetings: Jacksonville Jaguars 3, Indianapolis Colts 1.
JAXJacksonville Jaguars@
INDIndianapolis Colts23–17JAXINDIndianapolis Colts@JAXJacksonville Jaguars19–36JAXJAXJacksonville Jaguars@INDIndianapolis Colts23–26INDINDIndianapolis Colts@JAXJacksonville Jaguars34–37JAXNext scheduled meeting: Indianapolis Colts at Jacksonville Jaguars on Nov 1, 2026 at 1:00 PM ET. Lines post as the game approaches.
