This matchup is not live right now. NFL spreads, totals, the community lean, and player props post as each game approaches. In the meantime:
Buffalo Bills and New England Patriots last played on Sunday, Dec 14, 2025, when the Buffalo Bills won 35–31. The last 4 meetings are split 2-2.
BUFBuffalo Bills@
NENew England Patriots35–31BUFNENew England Patriots@BUFBuffalo Bills23–20NEBUFBuffalo Bills@NENew England Patriots16–23NENENew England Patriots@BUFBuffalo Bills21–24BUFNext scheduled meeting: New England Patriots at Buffalo Bills on Oct 4, 2026 at 1:00 PM ET. Lines post as the game approaches.
