This matchup is not live right now. NFL spreads, totals, the community lean, and player props post as each game approaches. In the meantime:
Kansas City Chiefs and Buffalo Bills last played on Sunday, Nov 2, 2025, when the Buffalo Bills won 28–21. Over the last 2 meetings: Buffalo Bills 2, Kansas City Chiefs 0.
KCKansas City Chiefs@
BUFBuffalo Bills21–28BUFKCKansas City Chiefs@BUFBuffalo Bills21–30BUFNext scheduled meeting: Kansas City Chiefs at Buffalo Bills on Nov 26, 2026 at 8:20 PM ET. Lines post as the game approaches.
© 2026 BettorEdge.
