This matchup is not live right now. NFL spreads, totals, the community lean, and player props post as each game approaches. In the meantime:
Seattle Seahawks and San Francisco 49ers last played on Saturday, Jan 3, 2026, when the Seattle Seahawks won 13–3. The last 4 meetings are split 2-2.
SEASeattle Seahawks@
SFSan Francisco 49ers13–3SEASFSan Francisco 49ers@SEASeattle Seahawks17–13SFSEASeattle Seahawks@SFSan Francisco 49ers20–17SEASFSan Francisco 49ers@SEASeattle Seahawks36–24SFNext scheduled meeting: San Francisco 49ers at Seattle Seahawks on Oct 11, 2026 at 4:25 PM ET. Lines post as the game approaches.
